RSS | Stroke / ictus

Feed aggiornato con le ultime pubblicazioni scientifiche da PubMed su ictus ischemico ed emorragico, trombolisi, trombectomia, gestione preospedaliera e intraospedaliera, prevenzione secondaria e innovazioni terapeutiche. Uno strumento utile per restare informati sui progressi nella diagnosi e nel trattamento dell’ictus in medicina d’urgenza.

Stroke / ictus

When Clinical Judgment Goes Beyond Balance, Eyes, Face, Arm, Speech (BEFAST): Acute Confusion Prompting Stroke Code Activation in Dominant Hemisphere Large Vessel Occlusion 29 Agosto 2026
Acute ischemic stroke can present with atypical features, including confusion, disorientation, or other cortical manifestations that may not be captured by commonly used stroke recognition tools such as Balance, Eyes, Face, Arm, Speech (BEFAST), posing a diagnostic challenge in the emergency department and potentially delaying identification of large vessel occlusion (LVO) and reperfusion therapy. We […]
Humaid Sadiq
Incremental Prognostic Value of the C-Reactive Protein-to-Albumin Ratio Beyond a Parsimonious Clinical Reference Model in Critically Ill Patients with Acute Ischemic Stroke 27 Agosto 2026
Background and Objectives: The C-reactive protein-to-albumin ratio (CAR) is associated with mortality and poor outcome after acute ischemic stroke, but the association is not the same as added clinical usefulness. We evaluated whether admission CAR and follow-up CAR provide prognostic information beyond a prespecified parsimonious clinical reference model comprising age, neurological severity, and admission glucose […]
Hasan Burak Toprak
Low-Field and Portable MRI for Acute Ischemic Stroke: A Systematic Review 27 Agosto 2026
CONCLUSIONS: Low-field and portable MRI show promising diagnostic potential for AIS and TIA, particularly when conventional MRI is unavailable, delayed, or impractical. However, current evidence is limited by small, predominantly single-center studies with substantial risk of bias, and further prospective multicenter validation is required before these technologies can be incorporated into routine clinical decision-making.
Rachana R Borkar
Comparison of acute stroke care pathways and door-to-needle times in Belgian and Turkish university hospitals: A four-center retrospective study 27 Agosto 2026
CONCLUSION: Significant differences in DTN times were observed between EDs employing different models of care. In addition to physician-staffed prehospital care and direct IVT administration in the CT suite, locating the CT scanner within the ED was associated with shorter door-to-CT times. These findings can guide policymakers and clinicians to optimize stroke protocols.
Muhammet Fatih Beşer
Care Strategies in Emergency Management of Acute Ischemic Stroke: A Systematic Review 26 Agosto 2026
CONCLUSIONS: Critical treatment times in acute ischemic stroke are influenced by multiple factors, and targeted organizational and clinical strategies can accelerate diagnosis and treatment. Although improvements in clinical outcomes were not consistently demonstrated across all included studies, the available evidence consistently supports protocol-driven multidisciplinary emergency care as an effective strategy for reducing treatment delays and […]
Paula Sánchez-Fernandez
An interpretable machine learning framework with clinical nomogram for predicting in-hospital mortality in acute ischemic stroke using high-granularity bedside data 26 Agosto 2026
CONCLUSIONS: Integration of bedside nursing assessments with emergency and laboratory data into an ensemble gradient-boosting model markedly improves early in-hospital mortality prediction in AIS compared with established ICU scores.
Guoying Li
Impact of an eye-stroke protocol with non-mydriatic ocular imaging in an emergency department 14 Agosto 2026
CONCLUSION: Despite our Eye-Stroke protocol, facilitated by NFMP-OCT in our ED, only 16% of acute CRAO/BRAO eyes were diagnosed early enough to be considered for intravenous (IV) thrombolysis, which was administered to only 43% of those eligible. Rapid workup found a major cause of CRAO/BRAO in 72%, and 18% had concurrent cerebral infarctions on MRI. […]
Madhuri Akella
Aligning emergency admission and stroke center catchment areas: Association with intravenous thrombolysis rates 12 Agosto 2026
CONCLUSION: Co-location of the PSC and ED was associated with higher IVT rates, particularly among EMS-transported emergency-call patients, suggesting that alignment of emergency admission pathways and stroke center catchment areas may improve access to time-critical reperfusion therapy.
Martin Faurholdt Gude
Neuroanatomical correlates of stroke-related dizziness and vertigo: secondary analysis from the INSPiRE-TMS trial 12 Agosto 2026
Dizziness and vertigo are common and debilitating neurological symptoms among patients visiting the emergency department (ED). Possibly because the symptoms are not captured by standard stroke severity tools such as the NIHSS (National Institutes of Health Stroke Scale), their network-level neuroanatomical correlates-particularly potential supratentorial contributions-remain incompletely characterized. Therefore, we aim to investigate the neuroanatomical substrates […]
Yunyou Tang
Diagnostic Performance of Mobile Low-Field MRI and CT for Acute Headache as the Isolated Clinical Manifestation in the Neurology Emergency Department 11 Agosto 2026
CONCLUSION: For emergency patients with headaches as the initial and isolated clinical manifestation, mLF-MRI may serve as a supplementary diagnostic imaging modality that provides additional diagnostic information in selected ED settings. mLF-MRI, especially FLAIR sequences, demonstrated high CT-referenced diagnostic concordance for SAH and may also detect early ischemic lesions.
Xinyan Hu
Bilateral internal carotid artery fibromuscular dysplasia identified during acute ischemic stroke evaluation: A case report 10 Agosto 2026
A 52-year-old woman with a known history of hypertension presented to the emergency department with acute confusion. She also had a prior history of transient ischemic attack. Computed tomography (CT) of the brain demonstrated an acute infarction involving the left insular cortex. CT angiography revealed no evidence of large-vessel occlusion; however, both cervical segments of […]
Wejdan Hashim AlMusallam
Concurrent cardiocerebral infarction in the emergency department: A case series from a tertiary care centre in South India 6 Agosto 2026
CONCLUSION: CCI is associated with high in-hospital mortality. These findings suggest that delayed presentation and limited eligibility for timely reperfusion may contribute to poor outcomes, particularly in patients with severe neurological involvement. In emergency settings, early recognition, rapid risk stratification, and coordinated multidisciplinary decision-making are critical for optimizing outcomes in this complex dual vascular emergency.
Thenemukil Jayajothi
Effect of Prehospital Time on Door-to-Computed Tomography Time in Acute Ischemic Stroke: A Multicenter Study 5 Agosto 2026
CONCLUSIONS: Decision-making delays and prehospital notification appear to be key determinants of door-to-CT time in the management of acute ischemic stroke.
Kuo-En Chen
Cardiac photon-counting detector computed tomography in acute ischemic stroke: diagnostic accuracy for detection of left atrial appendage thrombus 1 Agosto 2026
CONCLUSION: Cardiac PCD-CT integrated as part of the acute stroke imaging protocol is a promising diagnostic tool that may reliably exclude the presence of LAA thrombus.
Annemarie Kirschfink
Acute Stroke Care in a Thrombolysis-Capable Emergency Department in Iraq: Patient Characteristics, Risk Factors, and Reperfusion Metrics From a One-Year Registry 31 Luglio 2026
Background Stroke remains an important cause of death and long-term disability. Contemporary data on acute stroke care in Iraq remain limited. Objective This study aimed to describe patient characteristics, vascular risk factors, stroke subtypes, and reperfusion metrics among patients presenting with acute stroke to a thrombolysis-capable tertiary center in Iraq. Methods This retrospective observational study […]
Mustafa Al-Shahni
Stroke care - critical time metrics: does CT scanner placement in the emergency department matter? 31 Luglio 2026
No abstract
Parth Mohanty
Infantile Basal Ganglia Infarct due to Mineralizing Angiopathy: A Case Report 29 Luglio 2026
An 11-month-old female infant without any significant past medical history presented to an outside facility emergency department due to acute onset hemiparesis. Initial head CT imaging was negative for acute ischemic stroke (AIS). The patient was transferred to our children's hospital for further evaluation and management. Previous head imaging was read again by a pediatric […]
Ashley Strube
Diagnostic performance of magnetic resonance imaging in suspected stroke: Strengths, weaknesses, and clinical correlates 29 Luglio 2026
CONCLUSIONS: In non-comprehensive stroke care with an MRI-first approach, MRI is moderately sensitive and highly specific for stroke and TIA, and its performance varies depending on the clinical context.
Malini Vendela Sagar
Latent profile analysis of emergency department presentation characteristics in patients with acute ischemic stroke 24 Luglio 2026
CONCLUSION: Emergency presentation patterns among AIS patients exhibit significant heterogeneity, allowing classification into four latent profiles with distinct behavioral characteristics. Patients across profiles demonstrate marked differences in presentation efficiency, stroke knowledge levels, and clinical outcomes. Latent profile classification independently predicts functional prognosis beyond traditional clinical confounders. Developing stratified intervention strategies based on core...
Xiangguang Yin
Patient and hospital factors associated with disparities in acute stroke treatment in community and academic hospitals 22 Luglio 2026
CONCLUSION: Patient-level factors and hospital setting were associated with differences in acute care suggesting opportunities for community outreach on EMS use, interventions to alleviate language barriers, and a need to address systemic biases.
Jerry Shen