RSS | Intossicazioni / overdose

Un feed aggiornato quotidianamente con gli ultimi articoli pubblicati su PubMed relativi a intossicazioni acute, overdose da sostanze d’abuso, farmaci o agenti chimici. Uno strumento utile per rimanere costantemente informati su nuovi approcci diagnostici, gestione clinica, trattamenti emergenti e protocolli internazionali, fondamentali nella pratica dell’emergenza-urgenza.

Intossicazioni / overdose

Health-Care Access and Unmet Needs Among Sexual and Gender Minorities Engaging in Chemsex: A Scoping Review 2 Settembre 2026
CONCLUSIONS: This scoping review enhances comprehension of health-care services targeting chemsex practices. Gaining insight into health-care access and unmet needs is essential to guide future drug policy and advocacy efforts.
Xi-Yuan Peng
Incidence, Prevalence, and Risk Factors of Dog Bites in Pediatric Populations: Protocol for a Systematic Review 2 Settembre 2026
CONCLUSIONS: By aggregating data across diverse populations and settings, this systematic review will deliver the most comprehensive global assessment of pediatric dog-bite epidemiology to date, stratified by age group, geographic region, sex, and socioeconomic context, with direct implications for reducing the burden of these preventable injuries worldwide.
Nathaniel LaBarre
Navigating Consent and Confidentiality in Adolescent Substance Use Treatment 2 Settembre 2026
Consent and confidentiality are central to adolescent substance use care, functioning not only as legal and ethical frameworks but as early preventive interventions during a critical developmental window. This urgency is highlighted by rising rates of substance use disorders and overdose deaths driven by illicit fentanyl and polysubstance exposure. Expanded harm reduction efforts have intensified […]
Sabihul Alam
Early biomarker prognostic signals for 30-day mortality in acute poisoning: exploratory analysis of a complete-case subgroup from a derived MIMIC-IV dataset 2 Settembre 2026
Reliable early prognostic tools for acute poisoning remain limited. This study examined whether four first-measured routine biomarkers - glucose, lactate, bicarbonate, and white blood cell count (WBC) - carry prognostic signal for 30-day mortality in emergency department (ED) patients with acute poisoning, using a pre-processed, de-identified electronic health records dataset derived from MIMIC-IV (Medical Information […]
Ramazan Sami Aktaş
Responding to medetomidine in Philadelphia: narrative summary of the public health response to a new psychoactive substance 1 Settembre 2026
CONCLUSION: The insights gained regarding medetomidine withdrawal management will be shared with community organizations providing services to people who use drugs in Philadelphia and clarify specific barriers and areas for ongoing support. Other communities experiencing shifts in drug supply may benefit from this knowledge and similar information sharing colloquiums.
TaReva Warrick-Stone
Gabapentinoid Poisoning Presentations to Victorian Emergency Departments: A 15-Year Trend Analysis 1 Settembre 2026
This study identified and characterised 1207 emergency department presentations related to gabapentinoid overdose in Victoria from 2009-2010 to 2023-2024. Presentation rates increased substantially since 2009-2010, and about half (49.5%; 597/1207) of all presentations were classified as intentional. Co-ingestants were common, although 36.2% (437/1207) of presentations were reported to involve gabapentinoids alone.
Bishaal Tej Gurung
Rethinking responses to over-the-counter drug overdose among young people in Japan: Toward a low-threshold support architecture 31 Agosto 2026
Over-the-counter (OTC) drug misuse and overdose among young people in Japan should be understood not only as a medication-safety issue but also as a public health and youth support issue situated at the intersection of psychological distress, self-harm, suicidality, help-seeking difficulties, digital environments, and fragmented care systems. Current responses, including emergency treatment for acute intoxication, […]
Masana Ujihara
Buprenorphine Dispensed by Pharmacies and Administered in Emergency Departments in Urban and Rural Areas - United States, 2019-2025 27 Agosto 2026
Drug overdose deaths remain a major public health concern in the United States. Although buprenorphine is approved by the Food and Drug Administration to treat opioid use disorder and reduces overdose risk and deaths, the medication remains underused in the United States, and many persons who could benefit from treatment lack access. This report describes […]
Gery P Guy
Neuroleptic Malignant Syndrome 27 Agosto 2026
Neuroleptic malignant syndrome (NMS) is a rare but potentially life-threatening neurological emergency, most commonly associated with antipsychotic drugs and other dopamine receptor-blocking agents. Although its incidence has declined over recent decades, NMS remains a diagnostic challenge due to its heterogeneous clinical presentation and overlap with other drug-induced syndromes. The classic clinical picture is defined by […]
Paula Ivarola
Maximizing Opioid Restitution Funds via a Networked Care Approach: The Baltimore Comprehensive Overdose Response to End the Epidemic (BCORE) Program 26 Agosto 2026
Opioid use disorder and overdose are significant public health crises. Treatments for opioid overdose are highly successful yet also extremely decentralized and difficult for patients who are interested in treatment to navigate. Decentralization also slows progress with scaling treatment access and reducing overdose. This Commentary discusses establishment of the Baltimore Comprehensive Overdose Response to End […]
Martha O Jurczak
Yellow Granular Material in Hair: A Bedside Clue to Overdose from Cold Medication Containing Acetaminophen 26 Agosto 2026
CASE PRESENTATION: A 28-year-old woman was brought to the emergency department after being found collapsed at home. Because she was unable to provide a history, contextual bedside clues were important during the initial assessment. Bright yellow granular material with a medicinal odor was noted adherent to her hair. This unusual finding raised suspicion of overdose […]
So Sakamoto
Corrigendum to "Proportion of fentanyl reports in illicit drug seizures and nonfatal overdose emergency department visits in the United States, 2021-2024" [International Journal of Drug Policy 155 (2026) 105382] 26 Agosto 2026
No abstract
Mehrdad Khezri
Web Monitoring as an Early Warning System: "Benadryl Challenge" Online Mentions Correlate With Diphenhydramine Overdoses Reported to US Poison Centers 26 Agosto 2026
CONCLUSIONS: PC call volume and web mentions demonstrate a reciprocal relationship and PC call volume remained elevated for over 25 days after the spike in web mentions. Emergency services/departments and public health efforts can be informed real-time by these relationships as an early warning to healthcare facilities and professionals and may justify integration within these […]
Jacob Altholz
Methadone vs Buprenorphine-Naloxone in Opioid Overdose Survivors 25 Agosto 2026
CONCLUSIONS AND RELEVANCE: In this matched cohort of individuals with a past-year opioid overdose, starting methadone was associated with a reduced risk of death during the subsequent year compared with starting buprenorphine-naloxone. Treatment durations were short, particularly among individuals starting buprenorphine-naloxone, and there was no significant difference in mortality during receipt of opioid agonist treatment. […]
Robert A Kleinman
Kratom Toxicity: Pharmacologic Mechanisms, Clinical Risks, and Management Considerations 24 Agosto 2026
Kratom (Mitragyna speciosa) is an opioid-like botanical increasingly used for self-management of pain and opioid withdrawal and has been increasingly implicated in emergency department presentations for acute toxicity. Despite its growing use, kratom remains poorly understood in clinical practice, particularly with respect to its complex, metabolite-dependent pharmacology. Product heterogeneity, variable alkaloid composition, and frequent polysubstance […]
Asis A Babun
Acetaminophen Overdose and Self-Induced Ethanol Enema 24 Agosto 2026
Ethanol is most commonly consumed orally, although rare cases of intentional rectal administration have been described. We present the case of a 37-year-old man who presented to the emergency department following intentional rectal administration of ethanol and a concomitant acetaminophen overdose with extensive review of literature. This unusual presentation highlights the diagnostic and management challenges […]
Amisha Ghotra
Harm Reduction on Campus: A National Survey of Collegiate-based EMS Agencies 24 Agosto 2026
CONCLUSIONS: Despite heterogeneity in operational structures, respondents demonstrated readiness for opioid overdose reversal, with naloxone stocked in nearly all agency gear bags, and established educational outreach including public CPR training and naloxone education. However, adoption of broader harm reduction strategies remained limited. Systemic barriers limited expansion of harm reduction programming. Coordinated institutional investment and standardized […]
Patryk A Dabek
Verapamil-sensitive fascicular ventricular tachycardia precipitated by promethazine overdose 24 Agosto 2026
Verapamil-sensitive fascicular tachycardia is a type of ventricular tachycardia (VT) involving the specialised cardiac conducting tissue. Drug overdose is an important cause to consider when assessing patients with a new presentation of a broad complex tachycardia. Multiple antihistamines have been implicated as pro-arrhythmic, but these tend to precipitate Torsades de Pointes via drug-induced QT prolongation. […]
Salma Hassan
Clinical Decision Support and the Naloxone Equity Exception: Insights from an Emergency Department 21 Agosto 2026
INTRODUCTION: Despite rising overdose mortality nationwide, racial and ethnic disparities in naloxone access persist. This study examined whether these disparities remained after adjusting for demographic and clinical risk factors, including an electronic health record-based Clinical Decision Support alert, within an emergency department setting.
Aretha D Miller
Emergency department diagnosis and management of acetaminophen or salicylate toxicity 21 Agosto 2026
Acetaminophen and salicylate are among the most widely used nonprescription analgesics and are common causes of toxic medication overdose. Diagnostic and management approaches differ depending on whether toxicity results from a single acute ingestion or chronic supratherapeutic use. Although acetaminophen and salicylate toxicity are well studied, controversies remain regarding management. This review presents a systematic […]
Linda Johnson